AR Signaling in Human Malignancies: Prostate Cancer and Beyond
by Emmanuel S. Antonarakis (ed.)
Publisher: MDPI AG 2018
Number of pages: 246
This Issue initially reviews the role of AR in advanced prostate cancer, and then explores the potential importance of AR signaling in other epithelial malignancies. The first few articles focus on the use of novel AR-targeting therapies in castration-resistant prostate cancer and the mechanisms of resistance to novel antiandrogens, and they also outline the interaction between AR and other cellular pathways, including PI3 kinase signaling, transcriptional regulation, angiogenesis, stromal factors, Wnt signaling, and epigenetic regulation in prostate cancer.
Home page url
Download or read it online for free here:
by Vera C. Mazurak (ed.) - MDPI AG
The development and treatment of cancer presents a complex interaction between tumor and host. The provision of nutrients provides substrates and signals for immunity, tumor metabolism and the protection of the host from treatment toxicities.
by Momna Hejmadi - BookBoon
A short primer on how cancers develop and grow, and a gentle exploration of the fundamental concepts, using examples and key figures for illustration. The book explains six basic principles that inform our current understanding of cancer.
- American College of Medical Genetics
The Guidelines have been prepared to help the primary care provider to participate in the pre- and post-test education and counseling required for every patient contemplating genetic testing for breast and ovarian cancer.
- National Collaborating Centre for Cancer
Prostate cancer is one of the commonest cancers in men. There is evidence of practice variation around the country and of patchy availability of certain treatments. The guideline will help to address these issues and offer guidance on best practice.