AR Signaling in Human Malignancies: Prostate Cancer and Beyond
by Emmanuel S. Antonarakis (ed.)
Publisher: MDPI AG 2018
ISBN-13: 9783038427391
Number of pages: 246
Description:
This Issue initially reviews the role of AR in advanced prostate cancer, and then explores the potential importance of AR signaling in other epithelial malignancies. The first few articles focus on the use of novel AR-targeting therapies in castration-resistant prostate cancer and the mechanisms of resistance to novel antiandrogens, and they also outline the interaction between AR and other cellular pathways, including PI3 kinase signaling, transcriptional regulation, angiogenesis, stromal factors, Wnt signaling, and epigenetic regulation in prostate cancer.
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